Topographic Change Analysis (TCA)

You Can’t Call it Progression Until You do the Math

Accurately detects and monitors structural change
Automatic image alignment
Statistically significant change analysis
Tracks area and volume change
100% compatible with earlier HRT data
Change Probability Map for optic disc and peripapillary RNFL
Does not rely on a contour line or reference plane

Glaucoma Progression

Proven by 10-Year Follow-Up to Accurately Measure Progression

Topographic Change Analysis (TCA) is a statistically-based progression algorithm that accurately detects structural change over time by comparing variability between examinations and providing a statistical indicator of change.

HRT’s exclusive TCA technology automatically aligns subsequent images with the baseline examination, providing a point-by-point analysis of the optic disc and peripapillary RNFL.

Automatic Image Alignment

Image registration is the process of aligning images from multiple examinations and is essential for progression analysis. The HRT is the only imaging device that can automatically align scans, test for variability and identify areas of significant and reproducible change.

Confident Disease Management

To confidently manage the ongoing treatment of glaucoma patients, accurately tracking and measuring the progression of the disease is a must. Unlike other technologies that rely on simple comparison, the HRT utilizes TCA to apply statistical analysis that can help differentiate true biological change from random variability.

Compatibility with earlier software versions enables Heidelberg Engineering to validate algorithm performance against a large database of glaucoma cases with 10 years of follow-up. The HRT is the only imaging technology that is fully backwardly compatible.